Chemical Synthesis Methods And CDDO/CDDO-EA Preparations
Description
Triterpenoids are used for medicinal purposes in many Asian countries for anti-inflammatory, antipyretic, analgesic, hepatoprotective, cardiotonic, sedative and tonic effects. This invention presents an improves method for terpenoid synthesis.
Problem
Synthesis protocols of triterpenoids have been reported to require extremely complicated multi-step processes, are time intensive, and lack in specificity for desired, sufficiently pure products, rendering the techniques inefficient and less suitable for commercially scalable production of pharmacologically active terpenoids.
Solution
The present technology presents improved chemical synthesis strategies for producing pharmacologically active preparations of terpenoid derivatives, such as CDDO CDDO-Me, CDDO-EA, CDDO-Imand other CDDO derivatives and analogs, from oleanolic acid, in shorter time than previously reported.
Value Proposition
This invention presents an improved, low cost, time saving, commercially scalable process for synthesizing a pharmacologically active synthetic triterpenoid CDDO and its derivatives and analogs, from oleanolic acid.
Competitive Advantages
- Cost effective
- Shorter synthesis time
- Increased efficiency compared to other production methods
- Commercially scalable production process
Status of Development
Seeking commercial partners
IP Status
- Patent application filed
- Licensing available
