Polyolefin Fibers for Skin Regeneration and Implant
Description
This invention uses melt-spun polyolefin fine fibers to develop a new kind of nanofibrous surgical mesh suited for skin regeneration and mesh implantation. The material may be used as a scaffold in tissue engineering, wound dressing, hernia repair, pelvic organ prolapse support, cardiac patches, and as a coating for different implantable medical devices that need to be integrated within the body.
Problem
Polypropylene (PP) surgical mesh has been utilized extensively for wound healing applications due to its tensile strength properties. Despite this, PP surgical mesh shows a high rate of rejection by the body, approaching 40% of patients implanted.
Solution
The invention provides a novel means to avoid the high rate of rejection of PP surgical mesh by providing a nanofiber environment that promotes, rather than inhibits, cell growth and wound healing.
Value Proposition
- The novel invention uses the application of Forcespinning ™ technology to provide supports for robust cell proliferation and growth.
- The results has shown to improve faster wound healing time over the conventional PP surgical mesh.
Competitive Advantages
- Improved patient outcome through increased cell proliferation
and healing - Re-purposing of proven Forcespinning™ technology
- Easy to manufacture small-gauge nanofiber mats and treat with antibacterial/ antifungal properties
Status of Development
Lab prototype successful
IP Status
- Patent pending US20200289249A1
- Licensing Available
