Harald H. Göring Ph.D.

Faculty Profile Picture

Bennett Dyke & Jean MacCluer Endowed Professor

South Texas Diabetes and Obesity Institute & Department of Human Genetics

School of Medicine

Office: San Antonio Technology Center, Room 320.10
3463 Magic Drive
San Antonio, TX.  78229
Phone: +1 (210)-585-9771
Email: harald.goring@utrgv.edu

Education

2000 Ph.D. Statistical Genetics, Columbia University, New York, NY, USA
1996 M.Ph. Statistical Genetics, Columbia University, New York, NY, USA
1993 M.A. Molecular Genetics, Columbia University, New York, NY, USA

Research Focus

To what degree do we inherit predisposition to disease, life expectancy, and personal skills, predilections, and behaviors?  What are the specific genetic factors involved in shaping these characteristics?  To address these questions, Dr. Göring’s research group works on two aspects of genetic epidemiology, the development of statistical methods for genetic analysis and the application of those methods to well-designed human datasets.

On the methodological front, Dr. Göring’s research group is working on ways to localize and identify rare genomic variants with strong phenotypic impact on complex traits in extended pedigree samples. Specifically, his research group is taking advantage of genotyped rare variants from whole genome sequence data to phase and impute missing genotype data, and, they are developing methods for assessing the phenotypic effect of unique chromosome segments (found only in a single pedigree founder and his/her descendants) on disease and disease-related quantitative risk factors.

On the applied front, Dr. Göring’s research group is involved in several studies that integrate genotypic data and other “omics” technology-generated data to unravel trait etiology.  One project involves the search for differences in gene expression between schizophrenic individuals and controls.  His research group is examining the expression patterns of case and control lymphoblastoid cell lines (from both European ancestry and African American individuals) before and after stimulation with the neurotransmitter dopamine, with the hope that the identified differences reveal information about the etiology of schizophrenia.

Dr. Göring’s group is also seeking to identify early metabolomic biomarkers for type 2 diabetes.  They are screening prospectively collected blood plasma samples in a large cohort of Mexican American family members using a highly sensitive separation methodology (untargeted two-dimensional gas chromatography approach coupled to time-of-flight mass spectrometry) to identify specific molecules or chemical signatures that predict elevated risk of disease onset. In addition, he is assessing the genetic architecture that regulates the levels of specific individual compounds (or their ratios) in the blood stream.

    

Intramural Appointments

    

Extramural Appointments


  • Member, Special Emphasis Panel/Scientific Review Group Cancer, Cardiovascular and Sleep Epidemiology Panel B

Publication Highlights

  • Göring HHH, Ott J (1997) Relationship estimation in affected sib pair analysis of late-onset diseases. Eur J Hum Genet 5:69–77
  • Göring HHH, Terwilliger JD (2000) Linkage analysis in the presence of errors I: Complex-valued recombination fractions and complex phenotypes. Am J Hum Genet 66:1095–1106 [erratum in (2000) Am J Hum Genet 66:1472] doi: 10.1086/302797
  • Göring HHH, Terwilliger JD (2000) Linkage analysis in the presence of errors IV: Joint pseudomarker analysis of linkage and/or linkage disequilibrium on a mixture of pedigrees and singletons when the mode of inheritance cannot be accurately specified. Am J Hum Genet:1310–1327 doi: 10.1086/302845
  • Terwilliger JD, Göring HHH (2000) A review of gene mapping in the 20th and 21st centuries: Statistical methods, data analysis, and experimental design. Human Biology 72:63–132 doi: 10.3378/027.081.0615
  • Göring HHH, Terwilliger JD, Blangero J (2001) Large upward bias in estimation of locus-specific effects from genome-wide scans. Am J Hum Genet 69:1357–1369 doi: 10.1086/324471
  • Sigurdsson S, Nordmark G, Göring HHH, Lindroos K, Wiman A-C, Sturfelt G, Jönsen A, Rantapää-Dahlqvist S, Möller B, Kere J, Koskenmies S, Widén E, Eloranta M-L, Julkunen H, Kristjansdottir H, Steinsson K, Alm G, Rönnblom L, Syvänen AC (2005) Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus. Am J Hum Genet 76:528–537 doi: 10.1086/428480
  • Göring HHH, Curran JE, Johnson MP, Dyer TD, Charlesworth J, Cole SA, Jowett JBM, Abraham LJ, Rainwater DL, Comuzzie AG, Mahaney MC, Almasy L, MacCluer JW, Kissebah AH, Collier GR, Moses EK, Blangero J (2007) Discovery of expression QTLs using large-scale transcriptional profiling in human lymphocytes. Nat Genet 39:1208–1216 doi: 10.1038/ng2119
  • Ge B, Pokholok DK, Kwan T, Grundberg E, Morcos L, Verlaan DJ, Le J, Koka V, Lam KCL, Gagné V, Dias J, Hoberman R, Montpetit A, Joly MM, Harvey EJ, Sinnett D, Beaulieu P, Hamon R, Graziani A, Dewar K, Harmsen E, Majewski J, Göring HHH, Naumova AK, Blanchette M, Gunderson KL, Pastinen T (2009) Global patterns of cis-variation in human cells revealed by high-density allelic expression analysis. Nat Genet 41:1216–1222 doi: 10.1038/ng.473
  • Hiekkalinnaa T, Schäffer AA, Lambert B, Norrgrann P, Göring HHH, Terwilliger JD (2011) PSEUDOMARKER: A powerful program for joint linkage and/or linkage disequilibrium analysis on mixtures of singletons and related individuals. Hum Hered 71:256–266 doi: 10.1159/000329467
  • Rubicz R, Leach CT, Kraig E, Dhurandhar NV, Duggirala R, Blangero J, Yolken R, Göring HHH (2011) Genetic factors influence serological measures of common infections. Human Heredity 72:133–141 doi: 10.1159/000331220
  • Göring HHH (2012) Tissue specificity of genetic regulation of gene expression. Nature Genetics 44: 1077-1078 (invited commentary in News and Views) doi: 10.1038/ng.2420
  • Rubicz R, Yolken R, Drigalenko E, Carless MA, Dyer TD, Bauman L, Melton PE, Kent Jr JW, Harley JB, Duggirala R, Curran JE, Johnson MP, Cole SA, Almasy L, Moses EC, Dhurandhar NV, Kraig E, Blangero J, Leach CT, Göring HHH (2013) A genome-wide integrative genomic study localizes genetic factors influencing antibodies against Epstein-Barr virus nuclear antigen 1 (EBNA-1). PLoS Genetics 9:e1003147 doi: 10.1371/journal.pgen.1003147

Recent Publications

Book Chapters

  • Göring HH.  Gene expression studies and complex diseases.  Pp. 67-83. In: Genome Mapping and Genomics in Human and Non-Human Primates. R Duggirala, L Almasy, S Williams-Blangero, S Paul, C Kole (eds), Springer-Verlag Berlin Heidelberg, 2015.

Journal Articles

  • Kos MZ, Duan J, Sanders AR, Blondell L, Drigalenko EI, Carless MA, Gejman PV, Göring HHH; MGS. Dopamine perturbation of gene co-expression networks reveals differential response in schizophrenia for translational machinery. Transl Psychiatry. 2018 Dec 13;8(1):278. doi: 10.1038/s41398-018-0325-1. PMID: 30546022
  • Blondell L, Blackburn A, Kos MZ, Blangero J, Göring HHH. Contribution of Inbred Singletons to Variance Component Estimation of Heritability and Linkage. Hum Hered. 2018;83(2):92-99. doi: 10.1159/000492830. Epub 2018 Nov 2. PMID: 30391948
  • Knowles EEM, Mathias SR, Mollon J, Rodrigue A, Koenis MMG, Dyer TD,  Goring HHH, Curran JE, Olvera RL, Duggirala R, Almasy L, Blangero J, Glahn DC. A QTL on chromosome 3q23 influences processing speed in humans. Genes Brain Behav. 2018 Oct 31: e12530. doi: 10.1111/gbb.12530. [Epub ahead of print] PMID: 30379395
  • Duan J, Göring HHH, Sanders AR, Moy W, Freda J, Drigalenko EI, Kos M, He D, Gejman PV; MGS. Transcriptomic signatures of schizophrenia revealed by dopamine perturbation in an ex vivo model. Transl Psychiatry. 2018 Aug 16; 8(1):158. doi: 10.1038/s41398-018-0216-5. PMID: 30115913 (South Texas Diabetes and Obesity Institute)
  • Knowles EEM, Curran JE, Meikle PJ, Huynh K, Mathias SR, Göring HHH, VandeBerg JL, Mahaney MC, Jalbrzikowski M, Mosior MK, Michael LF, Olvera RL, Duggirala R, Almasy L, Glahn DC, Blangero J. Disentangling the genetic overlap between cholesterol  and suicide risk. Neuropsychopharmacology. 2018 Jul 23. doi: 10.1038/s41386-018-0162-1. [Epub ahead of print] PMID: 30082891 (South Texas Diabetes and Obesity Institute)
  •  Hsueh WC, Nair AK, Kobes S, Chen P, Göring HHH, Pollin TI, Malhotra A, Knowler WC, Baier LJ, Hanson RL. Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an  APOC3 Founder Mutation. Circ Cardiovasc Genet. 2017 Dec; 10(6). pii: e001809. doi: 10.1161/CIRCGENETICS.117.001809. PMID:29237685 (South Texas Diabetes and Obesity Institute)
  • Alexander-Bloch AF, Mathias SR, Fox PT, Olvera RL,  Göring HHH, Duggirala R, Curran JE, Blangero J, Glahn DC.  Human cortical thickness organized into genetically-determined communities across spatial resolutions.   Cereb Cortex. 2017 Nov 28:1-13. doi: 10.1093/cercor/bhx309. PMID: 29190330 (South Texas Diabetes and Obesity Institute)
  • Vasquez A, Ikram MK, Desrivières S, Vernooij MW, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beecham AH, Beiser A, Bernard M, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chen Q, Ching CR, Chouraki V, Cuellar-Partida G, Crivello F, Den Braber A, Doan NT, Ehrlich S, Giddaluru S, Goldman AL, Gottesman RF, Grimm O, Griswold ME, Guadalupe T, Gutman BA, Hass J, Haukvik UK, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Jørgensen KN, Karbalai N, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand AF, Matarin M, Mather KA, Mattheisen M, McKay DR, Milaneschi Y, Muñoz Maniega S, Nho K, Nugent AC, Nyquist P, Loohuis LM, Oosterlaan J, Papmeyer M, Pirpamer L, Pütz B, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Ropele S, Rose EJ, Royle NA, Rundek T, Sämann PG, Saremi A, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Trompet S, Vaidya D, Van der Grond J, Van der Lee SJ, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Wittfeld K, Woldehawariat G, Wolf C, Wolfers T, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Craen AJ, De Geus EJ, De Jager PL, De Zubicaray GI, Deary IJ, Debette S, DeCarli C, Delanty N, Depondt C, DeStefano A, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Enzinger C, Erk S, Espeseth T, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Fornage M, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL,  Göring HH, Green RC, Gruber O, Gudnason V, Guelfi S, Håberg AK, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Huentelman M, Pol HE, Ikeda M, Jack CR Jr, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon FJ, McMahon KL, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schmidt H, Schofield PR, Sigursson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Tsolaki M, Tzourio C, Uitterlinden AG, Hernández MC, Van der Brug M, van der Lugt A, van der Wee NJ, Van Haren NE, van 't Ent D, Van Tol MJ, Vardarajan BN, Vellas B, Veltman DJ, Völzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke RH, Zonderman AB, Martin NG, Van Duijn CM, Wright MJ, Longstreth WT, Schumann G, Grabe HJ, Franke B, Launer LJ, Medland SE, Seshadri S, Thompson PM, Ikram MA.  Novel genetic loci associated with hippocampal volume.   Nat Commun. 2017 Jan 18; 8:13624. doi: 10.1038/ncomms13624. PMID:28098162 (South Texas Diabetes and Obesity Institute)
  • Hodgson K, Almasy L, Knowles EE, Kent JW Jr, Curran JE, Dyer TD,  Göring HH, Olvera RL, Woolsey MD, Duggirala R, Fox PT, Blangero J, Glahn DC.  The genetic basis of the comorbidity between cannabis use and major depression.   Addiction. 2017 Jan;112(1):113-123. doi: 10.1111/add.13558. Epub 2016 Sep 26. PMID:27517884 (South Texas Diabetes and Obesity Institute)
  • Hodgson K, Carless MA, Kulkarni H, Curran JE, Sprooten E, Knowles EE, Mathias S,  Göring HHH, Yao N, Olvera RL, Fox PT, Almasy L, Duggirala R, Blangero J, Glahn DC.  Epigenetic age acceleration assessed with human white-matter images.   J Neurosci. 2017 May 3;37(18):4735-4743. doi: 10.1523/JNEUROSCI.0177-17.2017. Epub 2017 Apr 6. PMID:28385874 (South Texas Diabetes and Obesity Institute)
  • Hodgson K, Poldrack RA, Curran JE, Knowles EE, Mathias S,  Göring HHH, Yao N, Olvera RL, Fox PT, Almasy L, Duggirala R, Barch DM, Blangero J, Glahn DC.  Shared genetic factors influence head motion during MRI and Body Mass Index.   Cereb Cortex. 2017 Dec 1;27(12):5539-5546. doi: 10.1093/cercor/bhw321. PMID 27744290 (South Texas Diabetes and Obesity Institute)
  • Hsueh WC, Nair AK, Kobes S, Chen P,  Göring HHH, Pollin TI, Malhotra A, Knowler WC, Baier LJ, Hanson R.  Identity-by-Descent Mapping Identifies Major Locus for Serum Triglycerides in Amerindians Largely Explained by an APOC3 Founder Mutation.   Circ Cardiovasc Genet. 2017 Dec;10(6). pii: e001809. doi: 10.1161/CIRCGENETICS.117.001809 PMID: 29237685 (South Texas Diabetes and Obesity Institute)
  • Knowles EE, Huynh K, Meikle PJ,  Göring HH, Olvera RL, Mathias SR, Duggirala R, Almasy L, Blangero J, Curran JE, Glahn DC.  The lipidome in major depressive disorder: Shared genetic influence for ether-phosphatidylcholines, a plasma-based phenotype related to inflammation, and disease risk.   Eur Psychiatry. 2017 Feb 21; 43:44-50. doi: 10.1016/j.eurpsy.2017.02.479. [Epub ahead of print] PMID:28365467 (South Texas Diabetes and Obesity Institute)
  • Knowles EE, Meikle PJ, Huynh K,  Göring HH, Olvera RL, Mathias SR, Duggirala R, Almasy L, Blangero J, Curran JE, Glahn DC.  Serum phosphatidylinositol as a biomarker for bipolar disorder liability.   Bipolar Disord. 2017 Mar;19(2):107-115. doi: 10.1111/bdi.12468. Epub 2017 Feb 23. PMID:28230325 (South Texas Diabetes and Obesity Institute)
  • Kos MZ, Carless MA, Peralta J, Curran JE, Quillen EE, Almeida M, Blackburn A, Blondell L, Roalf DR, Pogue-Geile MF, Gur RC,  Göring HHH, Nimgaonkar VL, Gur RE, Almasy L.  Exome sequences of multiplex, multigenerational families reveal schizophrenia risk loci with potential implications for neurocognitive performance.   Am J Med Genet B Neuropsychiatr Genet. 2017 Dec;174(8):817-827. doi: 10.1002/ajmg.b.32597. Epub 2017 Sep 13. PMID: 28902459 (South Texas Diabetes and Obesity Institute)
  • Lake NJ, Taylor RL, Trahair H, Harikrishnan KN, Curran JE, Almeida M, Kulkarni H, Mukhamedova N, Hoang A, Low H, Murphy AJ, Johnson MP, Dyer TD, Mahaney MC,  Göring HHH, Moses EK, Sviridov D, Blangero J, Jowett JBM, Bozaoglu K.  TRAK2, a novel regulator of ABCA1 expression, cholesterol efflux and HDL biogenesis.   Eur Heart J. 2017 Dec 21;38(48):3579-3587. doi: 10.1093/eurheartj/ehx315. PMID: 28655204 (South Texas Diabetes and Obesity Institute)
  • Sanders AR, Drigalenko EI, Duan J, Moy W, Freda J,  Göring HHH, Gejman PV.  Transcriptome sequencing study implicates immune-related genes differentially expressed in schizophrenia: new data and a meta-analysis.  Transl Psychiatry. 2017 Apr 18;7(4): e1093. doi: 10.1038/tp.2017.47. PMID:28418402 (South Texas Diabetes and Obesity Institute)
  • Weerasekera L, Rudnicka C, Sang QX, Curran JE, Johnson MP, Moses EK,  Göring HH, Blangero J, Hricova J, Schlaich M, Matthews VB.  ADAM19: A novel Target for Metabolic Syndrome in Humans and Mice.   Mediators Inflamm. 2017; 2017:7281986. doi: 10.1155/2017/7281986. Epub 2017 Feb 7. PMID:28265178 (South Texas Diabetes and Obesity Institute)
  • Adams HH, Hibar DP, Chouraki V, Stein JL, Nyquist PA, Rentería ME, Trompet S, Arias-Vasquez A, Seshadri S, Desrivières S, Beecham AH, Jahanshad N, Wittfeld K, Van der Lee SJ, Abramovic L, Alhusaini S, Amin N, Andersson M, Arfanakis K, Aribisala BS, Armstrong NJ, Athanasiu L, Axelsson T, Beiser A, Bernard M, Bis JC, Blanken LM, Blanton SH, Bohlken MM, Boks MP, Bralten J, Brickman AM, Carmichael O, Chakravarty MM, Chauhan G, Chen Q, Ching CR, Cuellar-Partida G, Braber AD, Doan NT, Ehrlich S, Filippi I, Ge T, Giddaluru S, Goldman AL, Gottesman RF, Greven CU, Grimm O, Griswold ME, Guadalupe T, Hass J, Haukvik UK, Hilal S, Hofer E, Hoehn D, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kasperaviciute D, Kim S, Klein M, Kraemer B, Lee PH, Liao J, Liewald DC, Lopez LM, Luciano M, Macare C, Marquand A, Matarin M, Mather KA, Mattheisen M, Mazoyer B, McKay DR, McWhirter R, Milaneschi Y, Mirza-Schreiber N, Muetzel RL, Maniega SM, Nho K, Nugent AC, Loohuis LM, Oosterlaan J, Papmeyer M, Pappa I, Pirpamer L, Pudas S, Pütz B, Rajan KB, Ramasamy A, Richards JS, Risacher SL, Roiz-Santiañez R, Rommelse N, Rose EJ, Royle NA, Rundek T, Sämann PG, Satizabal CL, Schmaal L, Schork AJ, Shen L, Shin J, Shumskaya E, Smith AV, Sprooten E, Strike LT, Teumer A, Thomson R, Tordesillas-Gutierrez D, Toro R, Trabzuni D, Vaidya D, Van der Grond J, Van der Meer D, Van Donkelaar MM, Van Eijk KR, Van Erp TG, Van Rooij D, Walton E, Westlye LT, Whelan CD, Windham BG, Winkler AM, Woldehawariat G, Wolf C, Wolfers T, Xu B, Yanek LR, Yang J, Zijdenbos A, Zwiers MP, Agartz I, Aggarwal NT, Almasy L, Ames D, Amouyel P, Andreassen OA, Arepalli S, Assareh AA, Barral S, Bastin ME, Becker DM, Becker JT, Bennett DA, Blangero J, van Bokhoven H, Boomsma DI, Brodaty H, Brouwer RM, Brunner HG, Buckner RL, Buitelaar JK, Bulayeva KB, Cahn W, Calhoun VD, Cannon DM, Cavalleri GL, Chen C, Cheng CY, Cichon S, Cookson MR, Corvin A, Crespo-Facorro B, Curran JE, Czisch M, Dale AM, Davies GE, De Geus EJ, De Jager PL, de Zubicaray GI, Delanty N, Depondt C, DeStefano AL, Dillman A, Djurovic S, Donohoe G, Drevets WC, Duggirala R, Dyer TD, Erk S, Espeseth T, Evans DA, Fedko IO, Fernández G, Ferrucci L, Fisher SE, Fleischman DA, Ford I, Foroud TM, Fox PT, Francks C, Fukunaga M, Gibbs JR, Glahn DC, Gollub RL,  Göring HH, Grabe HJ, Green RC, Gruber O, Gudnason V, Guelfi S, Hansell NK, Hardy J, Hartman CA, Hashimoto R, Hegenscheid K, Heinz A, Le Hellard S, Hernandez DG, Heslenfeld DJ, Ho BC, Hoekstra PJ, Hoffmann W, Hofman A, Holsboer F, Homuth G, Hosten N, Hottenga JJ, Pol HE, Ikeda M, Ikram MK, Jack CR Jr, Jenkinson M, Johnson R, Jönsson EG, Jukema JW, Kahn RS, Kanai R, Kloszewska I, Knopman DS, Kochunov P, Kwok JB, Lawrie SM, Lemaître H, Liu X, Longo DL, Longstreth WT Jr, Lopez OL, Lovestone S, Martinez O, Martinot JL, Mattay VS, McDonald C, McIntosh AM, McMahon KL, McMahon FJ, Mecocci P, Melle I, Meyer-Lindenberg A, Mohnke S, Montgomery GW, Morris DW, Mosley TH, Mühleisen TW, Müller-Myhsok B, Nalls MA, Nauck M, Nichols TE, Niessen WJ, Nöthen MM, Nyberg L, Ohi K, Olvera RL, Ophoff RA, Pandolfo M, Paus T, Pausova Z, Penninx BW, Pike GB, Potkin SG, Psaty BM, Reppermund S, Rietschel M, Roffman JL, Romanczuk-Seiferth N, Rotter JI, Ryten M, Sacco RL, Sachdev PS, Saykin AJ, Schmidt R, Schofield PR, Sigurdsson S, Simmons A, Singleton A, Sisodiya SM, Smith C, Smoller JW, Soininen H, Srikanth V, Steen VM, Stott DJ, Sussmann JE, Thalamuthu A, Tiemeier H, Toga AW, Traynor BJ, Troncoso J, Turner JA, Tzourio C, Uitterlinden AG, Hernández MC, Van der Brug M, Van der Lugt A, Van der Wee NJ, Van Duijn CM, Van Haren NE, Van T Ent D, Van Tol MJ, Vardarajan BN, Veltman DJ, Vernooij MW, Völzke H, Walter H, Wardlaw JM, Wassink TH, Weale ME, Weinberger DR, Weiner MW, Wen W, Westman E, White T, Wong TY, Wright CB, Zielke HR, Zonderman AB, Deary IJ, DeCarli C, Schmidt H, Martin NG, De Craen AJ, Wright MJ, Launer LJ, Schumann G, Fornage M, Franke B, Debette S, Medland SE, Ikram MA, Thompson PM.  Novel genetic loci underlying human intracranial volume identified through genome-wide association. Nat Neurosci. 2016 Dec;19(12):1569-1582. doi: 10.1038/nn.4398. Epub 2016 Oct 3. PMID:27694991(South Texas Diabetes and Obesity Institute)
  • Blangero J, Teslovich TM, Sim X, Almeida MA, Jun G, Dyer TD, Johnson M, Peralta JM, Manning A, Wood AR, Fuchsberger C, Kent JW Jr, Aguilar DA, Below JE, Farook VS, Arya R, Fowler S, Blackwell TW, Puppala S, Kumar S, Glahn DC, Moses EK, Curran JE, Thameem F, Jenkinson CP, DeFronzo RA, Lehman DM, Hanis C, Abecasis G, Boehnke M,  Göring H, Duggirala R, Almasy L; T2D-GENES Consortium.  Omics-squared: Human genomic, transcriptomic and phenotypic data for genetic analysis workshop 19.   BMC Proc. 2016 Oct 18;10(Suppl 7):71-77. eCollection 2016. PMID:27980614 (South Texas Diabetes and Obesity Institute)
  • Chittoor G, Kent JW Jr, Almeida M, Puppala S, Farook VS, Cole SA, Haack K,  Göring HH, MacCluer JW, Curran JE, Carless MA, Johnson MP, Moses EK, Almasy L, Mahaney MC, Lehman DM, Duggirala R, Comuzzie AG, Blangero J, Voruganti VS.  GWAS and transcriptional analysis prioritize ITPR1 and CNTN4 for a serum uric acid 3p26 QTL in Mexican Americans.   BMC Genomics. 2016 Apr 2; 17:276. doi: 10.1186/s12864-016-2594-5. PMID:27039371 (South Texas Diabetes and Obesity Institute)
  • Guillen-Ahlers H, Rao PK, Levenstein ME, Kennedy-Darling J, Perumalla DS, Jadhav AY, Glenn JP, Ludwig-Kubinski A, Drigalenko E, Montoya MJ,  Göring HH, Anderson CD, Scalf M, Gildersleeve HI, Cole R, Greene AM, Oduro AK, Lazarova K, Cesnik AJ, Barfknecht J, Cirillo LA, Gasch AP, Shortreed MR, Smith LM, Olivier M. HyCCAPP as a tool to characterize promoter DNA-protein interactions in Saccharomyces cerevisiae. Genomics. 2016 Jun;107(6):267-73. doi: 10.1016/j.ygeno.2016.05.002. Epub 2016 May 13. PubMed PMID: 27184763
  • Hodgson K, Almasy L, Knowles EE, Kent JW, Curran JE, Dyer TD,  Göring HH, Olvera RL, Fox PT, Pearlson GD, Krystal JH, Duggirala R, Blangero J, Glahn DC.  Genome-wide significant loci for addiction and anxiety.   Eur Psychiatry. 2016 Aug; 36:47-54. doi: 10.1016/j.eurpsy.2016.03.004. Epub 2016 Jun 16. PMID:27318301 (South Texas Diabetes and Obesity Institute)
  • Knowles EE, Kent JW Jr, McKay DR, Sprooten E, Mathias SR, Curran JE, Carless MA, de Almeida MA,  Göring HH, Dyer TD, Olvera RL, Fox PT, Duggirala R, Almasy L, Blangero J, Glahn DC.  Genome-wide linkage on chromosome 10q26 for a dimensional scale of major depression.   J Affect Disord. 2016 Feb; 191:123-31. doi: 10.1016/j.jad.2015.11.012. Epub 2015 Nov 17. PMID:26655122(South Texas Diabetes and Obesity Institute)
  • Kulkarni H, Mamtani M, Peralta JM, Diego V, Dyer TD,  Goring H, Almasy L, Mahaney MC, Williams-Blangero S, Duggirala R, Curran JE, Blangero J Lack of association between SLC30A8 variants and type 2 diabetes in Mexican American families.   J Diabetes Res. 2016;2016:6463214. Epub 2016 Nov 8. PMID:27896278 (South Texas Diabetes and Obesity Institute)
  • Kulkarni H, Mamtani M, Peralta J, Almeida M, Dyer TD,  Goring HH, Johnson MP, Duggirala R, Mahaney MC, Olvera RL, Almasy L, Glahn DC, Williams-Blangero S, Curran JE, Blangero J.  Soluble forms of intercellular and vascular cell adhesion molecules independently predict progression to type 2 diabetes in Mexican American families.   PLoS One. 2016 Mar 23;11(3): e0151177. doi: 10.1371/journal.pone.0151177. eCollection 2016. PMID:27007680 (South Texas Diabetes and Obesity Institute)
  • Mamtani M, Kulkarni H, Dyer TD,  Göring HH, Neary JL, Cole SA, Kent JW, Kumar S, Glahn DC, Mahaney MC, Comuzzie AG, Almasy L, Curran JE, Duggirala R, Blangero J, Carless MA.  Genome- and epigenome-wide association study of hypertriglyceridemic waist in Mexican American families.   Clin Epigenetics. 2016 Jan 20; 8:6. doi: 10.1186/s13148-016-0173-x. eCollection 2016. PMID:26798409 (South Texas Diabetes and Obesity Institute)
  • Mathias SR, Knowles EE, Kent JW Jr, McKay DR, Curran JE, de Almeida MA, Dyer TD,  Göring HH, Olvera RL, Duggirala R, Fox PT, Almasy L, Blangero J, Glahn DC.  Recurrent major depression and right hippocampal volume: A bivariate linkage and association study.   Hum Brain Mapp. 2016 Jan;37(1):191-202. doi: 10.1002/hbm.23025. Epub 2015 Oct 20. PMID:26485182 (South Texas Diabetes and Obesity Institute)
  • Runge CL, Indap A, Zhou Y, Kent JW Jr, King E, Erbe CB, Cole R, Littrell J, Merath K, James R, Rüschendorf F, Kerschner JE, Marth G, Hübner N,  Göring HH, Friedland DR, Kwok WM, Olivier M . Association of TMTC2 with human nonsyndromic sensorineural hearing loss JAMA Otolaryngol Head Neck Surg. 2016 Sep 1;142(9):866-872. Epub 2016 Jun 16. doi: 10.1001/jamaoto.2016.1444. PMID: 27311106. (Texas Biomedical Research Institute) 
  • Traurig M, Hanson RL, Marinelarena A, Kobes S, Piaggi P, Cole S, Curran JE, Blangero J,  Göring H, Kumar S, Nelson RG, Howard BV, Knowler WC, Baier LJ, Bogardus C.  Analysis of SLC16A11 variants in 12,811 American Indians: Genotype-obesity interaction for type 2 diabetes and an association with RNASEK expression.   Diabetes. 2016 Feb;65(2):510-9. doi: 10.2337/db15-0571. Epub 2015 Oct 20. PMID:26487785 (South Texas Diabetes and Obesity Institute)
  • Zhou Y, Zhu G, Charlesworth JC, Simpson S Jr, Rubicz R,  Göring HH, Patsopoulos NA, Laverty C, Wu F, Henders A, Ellis JJ, van der Mei I, Montgomery GW, Blangero J, Curran JE, Johnson MP, Martin NG, Nyholt DR, Taylor BV; ANZgene consortium.  Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis.   Mult Scler. 2016 Nov;22(13):1655-1664. Epub 2016 Jan 27. PMID:26819262 (South Texas Diabetes and Obesity Institute)
  • Benton MC, Lea RA, Macartney-Coxson D, Hanna M, Eccles DA, Carless MA, Chambers GK, Bellis C,  Göring HH, Curran JE, Harper JL, Gibson G, Blangero J, Griffiths LR. A phenomic scan of the Norfolk Island genetic isolate identifies a major pleiotropic effect locus associated with metabolic and renal disorder markers . PLoS Genet. 2015 Oct 16;11(10): e1005593. doi:10.1371/journal.pgen.1005593. eCollection 2015 Oct. PubMed PMID: 26474483; PubMed Central PMCID: PMC4608754.
  • Blackburn A, Almeida M, Dean A, Curran JE, Johnson MP, Moses EK, Abraham LJ, Carless MA, Dyer TD, Kumar S, Almasy L, Mahaney MC, Comuzzie A, Williams-Blangero S, Blangero J, Lehman DM,  Göring HH. Effects of copy number variable regions on local gene expression in white blood cells of Mexican Americans . Eur J Hum Genet. 2015 Sep;23(9):1229-35. doi: 10.1038/ejhg.2014.280. Epub 2015 Jan 14. PubMed PMID: 25585699; PubMed Central PMCID: PMC4538210.
  • Butte NF, Liu Y, Zakeri IF, Mohney RP, Mehta N, Voruganti VS,  Göring H, Cole SA, Comuzzie AG. Global metabolomic profiling targeting childhood obesity in the Hispanic population . Am J Clin Nutr. 2015 Aug;102(2):256-67. doi: 10.3945/ajcn.115.111872. Epub 2015 Jun 17. PubMed PMID: 26085512; PubMed Central PMCID: PMC4515872.
  • Dager AD, McKay DR, Kent JW Jr, Curran JE, Knowles E, Sprooten E,  Göring HH, Dyer TD, Pearlson GD, Olvera RL, Fox PT, Lovallo WR, Duggirala R, Almasy L, Blangero J, Glahn DC. Shared genetic factors influence amygdala volumes and risk for alcoholism . Neuropsychopharmacology. 2015 Jan;40(2):412-20. doi: 10.1038/npp.2014.187. Epub 2014 Jul 31. PubMed PMID: 25079289; PubMed Central PMCID: PMC4443955.
  • Duan J, Sanders AR, Moy W, Drigalenko EI, Brown EC, Freda J, Leites C,  Göring HH; MGS, Gejman PV. Transcriptome outlier analysis implicates schizophrenia susceptibility genes and enriches putatively functional rare genetic variants . Hum Mol Genet. 2015 Aug 15;24(16):4674-85. doi: 10.1093/hmg/ddv199. Epub 2015 May 28. PubMed PMID: 26022996; PubMed Central PMCID: PMC4512633.
  • Glahn DC, Williams JT, McKay DR, Knowles EE, Sprooten E, Mathias SR, Curran JE, Kent JW Jr, Carless MA,  Göring HH, Dyer TD, Woolsey MD, Winkler AM, Olvera RL, Kochunov P, Fox PT, Duggirala R, Almasy L, Blangero J. Discovering schizophrenia endophenotypes in randomly ascertained pedigrees Biol Psychiatry. 2015 Jan 1;77(1):75-83. doi: 10.1016/j.biopsych.2014.06.027. Epub 2014 Jul 21. PMID: 25168609 (Texas Biomedical Research Institute)
  • Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O, Guadalupe T, Hass J, Woldehawariat G, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kim S, Klein M, Kraemer B, Lee PH, Olde Loohuis LM, Luciano M, Macare C, Mather KA, Mattheisen M, Milaneschi Y, Nho K, Papmeyer M, Ramasamy A, Risacher SL, Roiz-Santiañez R, Rose EJ, Salami A, Sämann PG, Schmaal L, Schork AJ, Shin J, Strike LT, Teumer A, van Donkelaar MM, van Eijk KR, Walters RK, Westlye LT, Whelan CD, Winkler AM, Zwiers MP, Alhusaini S, Athanasiu L, Ehrlich S, Hakobjan MM, Hartberg CB, Haukvik UK, Heister AJ, Hoehn D, Kasperaviciute D, Liewald DC, Lopez LM, Makkinje RR, Matarin M, Naber MA, McKay DR, Needham M, Nugent AC, Pütz B, Royle NA, Shen L, Sprooten E, Trabzuni D, van der Marel SS, van Hulzen KJ, Walton E, Wolf C, Almasy L, Ames D, Arepalli S, Assareh AA, Bastin ME, Brodaty H, Bulayeva KB, Carless MA, Cichon S, Corvin A, Curran JE, Czisch M, de Zubicaray GI, Dillman A, Duggirala R, Dyer TD, Erk S, Fedko IO, Ferrucci L, Foroud TM, Fox PT, Fukunaga M, Gibbs JR,  Göring HH, Green RC, Guelfi S, Hansell NK, Hartman CA, Hegenscheid K, Heinz A, Hernandez DG, Heslenfeld DJ, Hoekstra PJ, Holsboer F, Homuth G, Hottenga JJ, Ikeda M, Jack CR Jr, Jenkinson M, Johnson R, Kanai R, Keil M, Kent JW Jr, Kochunov P, Kwok JB, Lawrie SM, Liu X, Longo DL, McMahon KL, Meisenzahl E, Melle I, Mohnke S, Montgomery GW, Mostert JC, Mühleisen TW, Nalls MA, Nichols TE, Nilsson LG, Nöthen MM, Ohi K, Olvera RL, Perez-Iglesias R, Pike GB, Potkin SG, Reinvang I, Reppermund S, Rietschel M, Romanczuk-Seiferth N, Rosen GD, Rujescu D, Schnell K, Schofield PR, Smith C, Steen VM, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Turner JA, Valdés Hernández MC, van 't Ent D, van der Brug M, van der Wee NJ, van Tol MJ, Veltman DJ, Wassink TH, Westman E, Zielke RH, Zonderman AB, Ashbrook DG, Hager R, Lu L, McMahon FJ, Morris DW, Williams RW, Brunner HG, Buckner RL, Buitelaar JK, Cahn W, Calhoun VD, Cavalleri GL, Crespo-Facorro B, Dale AM, Davies GE, Delanty N, Depondt C, Djurovic S, Drevets WC, Espeseth T, Gollub RL, Ho BC, Hoffmann W, Hosten N, Kahn RS, Le Hellard S, Meyer-Lindenberg A, Müller-Myhsok B, Nauck M, Nyberg L, Pandolfo M, Penninx BW, Roffman JL, Sisodiya SM, Smoller JW, van Bokhoven H, van Haren NE, Völzke H, Walter H, Weiner MW, Wen W, White T, Agartz I, Andreassen OA, Blangero J, Boomsma DI, Brouwer RM, Cannon DM, Cookson MR, de Geus EJ, Deary IJ, Donohoe G, Fernández G, Fisher SE, Francks C, Glahn DC, Grabe HJ, Gruber O, Hardy J, Hashimoto R, Hulshoff Pol HE, Jönsson EG, Kloszewska I, Lovestone S, Mattay VS, Mecocci P, McDonald C, McIntosh AM, Ophoff RA, Paus T, Pausova Z, Ryten M, Sachdev PS, Saykin AJ, Simmons A, Singleton A, Soininen H, Wardlaw JM, Weale ME, Weinberger DR, Adams HH, Launer LJ, Seiler S, Schmidt R, Chauhan G, Satizabal CL, Becker JT, Yanek L, van der Lee SJ, Ebling M, Fischl B, Longstreth WT Jr, Greve D, Schmidt H, Nyquist P, Vinke LN, van Duijn CM, Xue L, Mazoyer B, Bis JC, Gudnason V, Seshadri S, Ikram MA; Alzheimer’s Disease Neuroimaging Initiative; CHARGE Consortium; EPIGEN; IMAGEN; SYS, Martin NG, Wright MJ, Schumann G, Franke B, Thompson PM, Medland SE. Common genetic variants influence human subcortical brain structures . Nature. 2015 Apr 9;520(7546):224-9. doi: 10.1038/nature14101. Epub 2015 Jan 21. PubMed PMID: 25607358; PubMed Central PMCID: PMC4393366.
  • Jenkinson CP,  Göring HH,  Arya R, Blangero J, Duggirala R, DeFronzo RA.  Transcriptomics in type 2 diabetes: Bridging the gap between genotype and phenotype.   Genom Data. 2015 Dec 17; 8:25-36. doi: 10.1016/j.gdata.2015.12.001. eCollection 2016 Jun. PMID:27114903 (South Texas Diabetes and Obesity Institute)
  • Knowles EE, McKay DR, Kent JW Jr, Sprooten E, Carless MA, Curran JE, Almeida MA, Dyer TD,  Göring HH, Olvera RL, Duggirala R, Fox PT, Almasy L, Blangero J, Glahn DC. Pleiotropic locus for emotion recognition and amygdala volume identified using univariate and bivariate linkage . Am J Psychiatry. 2015 Feb 1;172(2):190-9. doi: 10.1176/appi.ajp.2014.14030311. Epub 2014 Oct 31. PubMed PMID: 25322361; PubMed Central PMCID: PMC4314438.
  • Kulkarni H, Kos MZ, Neary J, Dyer TD, Kent JW Jr,  Göring HH, Cole SA, Comuzzie AG, Almasy L, Mahaney MC, Curran JE, Blangero J, Carless MA.  Novel epigenetic determinants of type 2 diabetes in Mexican-American families.   Hum Mol Genet. 2015 Sep 15;24(18):5330-44. doi: 10.1093/hmg/ddv232. Epub 2015 Jun 22. PMID:26101197 (South Texas Diabetes and Obesity Institute)
  • Peters MJ, Joehanes R, Pilling LC, Schurmann C, Conneely KN, Powell J, Reinmaa E, Sutphin GL, Zhernakova A, Schramm K, Wilson YA, Kobes S, Tukiainen T; NABEC/UKBEC Consortium, Ramos YF,  Göring HH, Fornage M, Liu Y, Gharib SA, Stranger BE, De Jager PL, Aviv A, Levy D, Murabito JM, Munson PJ, Huan T, Hofman A, Uitterlinden AG, Rivadeneira F, van Rooij J, Stolk L, Broer L, Verbiest MM, Jhamai M, Arp P, Metspalu A, Tserel L, Milani L, Samani NJ, Peterson P, Kasela S, Codd V, Peters A, Ward-Caviness CK, Herder C, Waldenberger M, Roden M, Singmann P, Zeilinger S, Illig T, Homuth G, Grabe HJ, Völzke H, Steil L, Kocher T, Murray A, Melzer D, Yaghootkar H, Bandinelli S, Moses EK, Kent JW, Curran JE, Johnson MP, Williams-Blangero S, Westra HJ, McRae AF, Smith JA, Kardia SL, Hovatta I, Perola M, Ripatti S, Salomaa V, Henders AK, Martin NG, Smith AK, Mehta D, Binder EB, Nylocks KM, Kennedy EM, Klengel T, Ding J, Suchy-Dicey AM, Enquobahrie DA, Brody J, Rotter JI, Chen YD, Houwing-Duistermaat J, Kloppenburg M, Slagboom PE, Helmer Q, den Hollander W, Bean S, Raj T, Bakhshi N, Wang QP, Oyston LJ, Psaty BM, Tracy RP, Montgomery GW, Turner ST, Blangero J, Meulenbelt I, Ressler KJ, Yang J, Franke L, Kettunen J, Visscher PM, Neely GG, Korstanje R, Hanson RL, Prokisch H, Ferrucci L, Esko T, Teumer A, van Meurs JB, Johnson AD. The transcriptional landscape of age in human peripheral blood . Nat Commun. 2015 Oct 22; 6:8570. doi: 10.1038/ncomms9570. PubMed PMID: 26490707; PubMed Central PMCID: MC4639797.
  • Poldrack RA, Laumann TO, Koyejo O, Gregory B, Hover A, Chen MY, Gorgolewski KJ, Luci J, Joo SJ, Boyd RL, Hunicke-Smith S, Simpson ZB, Caven T, Sochat V, Shine JM, Gordon E, Snyder AZ, Adeyemo B, Petersen SE, Glahn DC, Reese Mckay D, Curran JE,  Göring HH, Carless MA, Blangero J, Dougherty R, Leemans A, Handwerker DA, Frick L, Marcotte EM, Mumford JA.  Long-term neural and physiological phenotyping of a single human.   Nat Commun. 2015 Dec 9; 6:8885. doi: 10.1038/ncomms9885. PMID:26648521 (South Texas Diabetes and Obesity Institute)
  • Rodriguez-Acevedo AJ, Ferreira MA, Benton MC, Carless MA,  Göring HH, Curran JE, Blangero J, Lea RA, Griffiths LR. Common polygenic variation contributes to risk of migraine in the Norfolk Island population . Hum Genet. 2015 Oct;134(10):1079-87. doi: 10.1007/s00439-015-1587-9. Epub 2015 Jul 29. PubMed PMID: 26220684.
  • Rubicz R, Yolken R, Drigalenko E, Carless MA, Dyer TD, Kent J Jr, Curran JE, Johnson MP, Cole SA, Fowler SP, Arya R, Puppala S, Almasy L, Moses EK, Kraig E, Duggirala R, Blangero J, Leach CT,  Göring HH. Genome-wide genetic investigation of serological measures of common infections . Eur J Hum Genet. 2015 Nov;23(11):1544-8. doi: 10.1038/ejhg.2015.24. Epub 2015 Mar 11. PubMed PMID: 25758998; PubMed Central PMCID: PMC4613484.
  • Skallerup P, Thamsborg SM, Jørgensen CB, Mejer H,  Göring HH, Archibald AL, Fredholm M, Nejsum P. Detection of a quantitative trait locus associated with resistance to infection with Trichuris suis in pigs . Vet Parasitol. 2015 Jun 15;210(3-4):264-9. doi: 10.1016/j.vetpar.2015.03.014. Epub 2015 Mar 27. PubMed PMID: 25858116.
  • Sprooten E, Gupta CN, Knowles EE, McKay DR, Mathias SR, Curran JE, Kent JW Jr, Carless MA, Almeida MA, Dyer TD,  Göring HH, Olvera RL, Kochunov P, Fox PT, Duggirala R, Almasy L, Calhoun VD, Blangero J, Turner JA, Glahn DC.  Genome-wide significant linkage of schizophrenia-related neuroanatomical trait to 12q24.   Am J Med Genet B Neuropsychiatr Genet. 2015 Dec;168(8):678-86. doi: 10.1002/ajmg.b.32360. Epub 2015 Oct 5. PMID:26440917 (South Texas Diabetes and Obesity Institute)
  • Winnier DA, Fourcaudot M, Norton L, Abdul-Ghani MA, Hu SL, Farook VS, Coletta DK, Kumar S, Puppala S, Chittoor G, Dyer TD, Arya R, Carless M, Lehman DM, Curran JE, Cromack DT, Tripathy D, Blangero J, Duggirala R,  Göring HH, DeFronzo RA, Jenkinson CP. Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES) . PLoS One. 2015 Apr 1;10(4): e0119941. doi: 10.1371/journal.pone.0119941. eCollection 2015. PubMed PMID: 25830378; PubMed Central PMCID: PMC4382323.
  • Wood AR, Tuke MA, Nalls M, Hernandez D, Gibbs JR, Lin H, Xu CS, Li Q, Shen J, Jun G, Almeida M, Tanaka T, Perry JR, Gaulton K, Rivas M, Pearson R, Curran JE, Johnson MP,  Göring HH, Duggirala R, Blangero J, McCarthy MI, Bandinelli S, Murray A, Weedon MN, Singleton A, Melzer D, Ferrucci L, Frayling TM. Whole-genome sequencing to understand the genetic architecture of common gene expression and biomarker phenotypes . Hum Mol Genet. 2015 Mar 1;24(5):1504-12. doi: 10.1093/hmg/ddu560. Epub 2014 Nov 6. PubMed PMID: 25378555; PubMed Central PMCID: PMC4321449.
  • Benton MC, Lea RA, Macartney-Coxson D, Hanna M, Eccles DA, Carless MA, Chambers GK, Bellis C,  Göring HH, Curran JE, Harper JL, Gibson G, Blangero J, Griffiths LR. A phenomic scan of the Norfolk Island genetic isolate identifies a major pleiotropic effect locus associated with metabolic and renal disorder markers. PLoS Genet. 2015 Oct 16;11(10): e1005593. doi: 10.1371/journal.pgen.1005593. eCollection 2015 Oct. PubMed PMID: 26474483; PubMed Central PMCID: PMC4608754.
  • Kulkarni H, Kos MZ, Neary J, Dyer TD, Kent JW Jr,  Göring HH, Cole SA, Comuzzie AG, Almasy L, Mahaney MC, Curran JE, Blangero J, Carless MA. Novel epigenetic determinants of type 2 diabetes in Mexican-American families. Hum Mol Genet. 2015 Sep 15;24(18):5330-44. doi: 10.1093/hmg/ddv232. Epub 2015 Jun 22. PubMed PMID: 26101197; PubMed Central PMCID: PMC4550817.
  • Kringel H, Thamsborg SM, Petersen HH,  Göring HH, Skallerup P, Nejsum P. Serum antibody responses in pigs trickle-infected with Ascaris and Trichuris: Heritabilities and associations with parasitological findings. Vet Parasitol. 2015 Jul 30;211(3-4):306-11. doi: 10.1016/j.vetpar.2015.06.008. Epub 2015 Jun 12. PubMed PMID: 26095952.
  • Glahn DC, Williams JT, McKay DR, Knowles EE, Sprooten E, Mathias SR, Curran JE, Kent JW Jr, Carless MA,  Göring HH, Dyer TD, Woolsey MD, Winkler AM, Olvera RL, Kochunov P, Fox PT, Duggirala R, Almasy L, Blangero J. Discovering schizophrenia endophenotypes in randomly ascertained pedigrees . Biol Psychiatry. 2015 Jan 1;77(1):75-83. doi: 10.1016/j.biopsych.2014.06.027. Epub 2014 Jul 21. PubMed PMID: 25168609; PubMed Central PMCID: PMC4261014.
  • Curran JE, Kumar S, Cromack DT, Hu SL, Coletta DK, Dyer TD, Arya R, Carless M, Tripathy D, Blangero J, Duggirala R,  Göring HH, DeFronzo RA, Jenkinson CP. Transcriptomic identification of ADH1B as a novel candidate gene for obesity and insulin resistance in human adipose tissue in Mexican Americans from the Veterans Administration Genetic Epidemiology Study (VAGES). (2015) World Biomedical Frontiers, Diabetes and Obesity Section ISSN; published online. ISSN: 2328-0166.

Collaborating Institutions

  • Baylor College of Medicine

  • Texas Biomedical Research Institute

  • UT Health Science Center San Antonio

  • Southwest Research Institute

  • University of Pennsylvania

  • Yale University

  • University of Helsinki and Finnish Public Health Institute
  • Columbia University
  • University of Chicago and Northshore University Health System