Mohammed Farooqui, Ph.D.
Mohammed Farooqui, Ph.D.
Professor
Office: ESCNE 4.635
mohammed.farooqui@utrgv.edu
Current Courses taught
BIOL 2402 Anatomy and Physiology II
BIOL 3405 Histology
BIOL 4316 Environmental Toxicology
BIOL 5316 Advanced Toxicology
Education
PhD, University of Illinois at Urbana - Champaign, 1979, Major: Entomology
MS, University of Illinois at Urbana - Champaign, 1975, Major: Entomology
MS, Andhra Pradesh Agricultural University, 1970, Major: Agriculture
BS, Andhra Pradesh Agricultural University, 1968, Major: Agriculture
Research Interest
My research focus is on the toxicity and metabolism of environmental and industrial chemicals such as pesticides and aliphatic nitriles. My doctoral dissertation research was on the toxicity and metabolism of DDT and its analogs in houseflies. My postdoctoral research involved toxicity and metabolism of acrylonitrile, a monomer of plastic products. This chemical agent was once used as a pesticide and is routinely used as a starting material for synthesis of various types of polymers. It is found to be an ulcerogen and a carcinogen in rodents. At UTRGV I continued my research on a related chemical agent methacrylonitrile and its toxicity and metabolism in mice, rats and gerbils. My research also involved some experiments on the toxicity of formaldehyde, role of glutathione, and effect of caffeine and various dosing vehicles on the toxicity and metabolism of aliphatic nitriles.
Selected Publications
Farooqui, M.Y.H. and A.E. Ahmed. 1982. Molecular interactions of Acrylonitrile and Potassium Cyanide with Rat Blood. Chem-Biol. Interact. 38, 145-159.
Ahmed, A.E. and M.Y.H. Farooqui. 1982. Comparative Toxicities of Aliphatic Nitriles. Toxicol. Lett. 12, 157-163.
Ahmed, A.E., M.Y.H. Farooqui, R.K. Upreti and O. Elshabrawy. 1982. Distribution and Covalent Interactions of 1-14C Acrylonitrile in Rats. Toxicology. 23, 159-175.
Farooqui, M.Y.H. and R.L. Metcalf. 1983. Comparative Metabolism of Six Ethoxychlor Analogs and DDT in DDT-Resistant and Susceptible Strains of the Housefly Musca domestica L. Pestic. Biochem. Physiol. 19, 210-220.
Farooqui, M.Y.H. and R.L. Metcalf. 1983. Penetrations and Excretion of Effective Ethoxychlor Analogs and DDT in DDT-Resistant and Susceptible Houseflies. Arch. Environ. Contam. Toxicol. 12, 489-497.
Ahmed, A.E., Farooqui, M.Y.H., R.K. Upreti and O. Elshabrawy. 1983. Comparative Toxicokinetics of 2,3 14-C and 1-14C Acrylonitrile in the Rat. J. Appl. Toxicol. 3, 39-47.
Farooqui, M.Y.H. 1983. Formaldehyde-A Toxicology Update. J. Appl. Toxicol.3, 264-266.
Farooqui, M.Y.H. and A.E. Ahmed. 1983. The Effects of Acrylonitrile on Hemoglobin and Red Cell Metabolism. J. Toxicol. Environ. Hlth. 12, 695-707.
Farooqui, M.Y.H. and A.E. Ahmed. 1983. In vivo Interactions of Acrylonitrile with Macromolecules in Rats. Chem.-Biol. Interact. 47, 363-371.
Farooqui, M.Y.H. and A.E. Ahmed. 1984. Circadian Periodicity of Tissue Glutathione and its Relationship with Lipid Peroxidation in Rats. Life Sci. 34, 2413-2418.
Ahmed, A.E., M.Y.H. Farooqui and N.M. Trieff. 1985. Nitriles. In: Bioactivation of Foreign Compounds. (Ed: M.W. Anders). Academic Press. New York. 485-518.
Forkert, P.G., Forkert, L., M.Y.H. Farooqui and E.S. Reynolds. 1985. Lung Injury and Repair: DNA Synthesis following 1,1-Dichloroethylene. Toxicology 36, 199-214.
Farooqui, M.Y.H., M.M. Mumtaz, B.I. Ghanayem and A.E. Ahmed. 1990. Hemoglobin Degradation, Lipid Peroxidation and Inhibition of Na+/K+-ATPase in Rat Erythrocytes Exposed to Acrylonitrile. J. Biochem. Toxicol. 5, 221-227
Mumtaz, M.M., M.Y.H. Farooqui, B.I. Ghanayem, S. Rajaraman, L. Frankenburg and A.E. Ahmed.1991.Studies on the Mechanism of Urotoxic Effects of N,N'-Dimethyl aminopropionitrile in Rats and Mice: 1. Biochemical and Morphologic Characterization of the Injury and its Relationship to Metabolism. J. Toxicol. Environ. Health 33, 1-17.
Ghanayem, B.I., M.Y.H. Farooqui, O. Elshabrawy, M.M. Mumtaz and A.E. Ahmed, 1991. Assessment of the Acute Acrylonitrile-Induced Neurotoxicity in Rats. Neurotoxicol. Teratol. 13, 499-502.
Mumtaz, M.M., M.Y.H. Farooqui, B.I. Ghanayem and A.E. Ahmed. 1991. The Urotoxic Effects of N, N'- Dimethylaminopropionitrile: 2. In vivo and in vitro Metabolism. Toxicol. Appl. Pharmacol.110, 61- 69.
Farooqui, M.Y.H., B. Ybarra, J. Piper and A. Tamez. 1995. Effect of Dosing Vehicle on the Toxicity and Metabolism of Unsaturated Aliphatic Nitriles. J. Appl. Toxicol. 15, 411- 420.
Mumtaz, M. M., Farooqui, M. Y. H., Cannon-Cook, E. P. and Ahmed, A. E. 1997. Propionitrile: Whole Body Autoradiography, Conventional Toxicokinetics and Metabolism Studies in Rats. Toxicology and Industrial Health 13: 1-16
Farooqui, M.Y.H., M. Trevino, and I. Garcia. 2010. Effect of Alcohol and Caffeine on the Toxicity and Metabolism of Methacrylonitrile. In Male Sprague Dawley rats. Res. Commun. Pharmacol.